USA:(540) 808-3925
China:400-117-0038
United States
Shopping Cart
Sign in \ Register
Z-VAD-FMK (CAS: 187389-52-2)
Catalog #:EBC51064
  SKU-Pack Size Availability Size Price
EBC51064-1ML In Stock 1mL(10mM in DMSO) $223.50 / $156.45
EBC51064-1MG In Stock 1mg $88.50 / $61.95
EBC51064-5MG In Stock 5mg $238.50 / $166.95
EBC51064-10MG In Stock 10mg $373.50 / $261.45
EBC51064-25MG In Stock 25mg $673.50 / $471.45
If you want to get a larger packsize, Please contact your local distributor or
email us atinfo@ebiocell.com
Please Select The Country You Are In To Find Your Local Distributor.
EbioCell Phone:(540) 808-3925
Imperial Business Park 4819 Emperor Boulevard, E-mail:order@ebiocell.com
United States Suite 408 Durham, NC 27703, USA Web:www.ebiocell.com
Product Information
Synonym(s) Z-VAD(OMe)-FMK
Chemical Name methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate
Application Z-VAD-FMK is Irreversible, cell-permeable, broad-spectrum caspase Inhibitor
CAS Number 187389-52-2
Purity ≥99.0%
Molecular Weight 467.49
Molecular Formula C₂₂H₃₀FN₃O₇
SMILES C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1
Target & IC50 caspase processing and apoptosis: IC50 = 0.0015 - 5.8 mM
Solubility DMSO : 100 mg/mL (213.91 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.1391 ml 10.6954 ml 21.3908 ml
5 mM 0.4278 ml 2.1391 ml 4.2782 ml
10 mM 0.2139 ml 1.0695 ml 2.1391 ml
50 mM 0.0428 ml 0.2139 ml 0.4278 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Z-VAD-FMK is an irreversible, cell-permeable, broad-spectrum caspase inhibitor. Z-VAD-FMK limited Fas-induced mouse liver damage and apoptosis to <1% and abrogated 7-hydroxystaurosporine and etoposide-induced apoptosis in HL60 cells at 50 μM.

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Copyright 2015 EbioCell, Inc. All Rights Reserved.  备案号:津ICP备2022005142号-1