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Caspase-5 Rabbit Monoclonal Antibody
Catalog #:EAB21779
  SKU-Pack Size Availability Size Price
EAB21779-100UL In Stock 100ul £251.90
If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com
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CUlabSciences Phone:+44 (0) 1232 330008
Cambridge House St Thomas' Place Ely, E-mail:sales@culabsciences.co.uk
United Kingdom Cambridge CB27 9RD UK Web:www.culabsciences.co.uk
Product Information
Applications WB, IP, IHC-P, IF/ICC
Species Reactivity Human
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000 
IP=1:10-100 
IHC-P=1:50-200 
IF/ICC=1:50-200 
MW (kDa) 47
Conjugate Unconjugate
Specificity Caspase-5 Rabbit Monoclonal Antibody detects endogenous levels of Caspase-5 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) CASP5; ICE(rel)III; ICEREL-III; ICH-3; ICH3
Gene Aliases CASP5
UniProt ID

P51878

Entrez Gene ID

838

Product Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.  

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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