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CDK4 Rabbit Monoclonal Antibody
Catalog #:EAB21774
  SKU-Pack Size Availability Size Price
EAB21774-100UL In Stock 100ul £251.90
EAB21774-200UL In Stock 200ul £405.90
If you want to get a larger packsize, Please contact your local distributor or
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CUlabSciences Phone:+44 (0) 1232 330008
Cambridge House St Thomas' Place Ely, E-mail:sales@culabsciences.co.uk
United Kingdom Cambridge CB27 9RD UK Web:www.culabsciences.co.uk
Product Information
Applications WB, IP, IF/ICC
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000 
IP=1:10-100 
IF/ICC=1:50-200 
MW (kDa) 34
Conjugate Unconjugate
Specificity CDK4 Rabbit Monoclonal Antibody detects endogenous levels of CDK4 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) CDK4; CMM3; PSK-J3; cyclin-dependent kinase 4
Gene Aliases CDK4
UniProt ID

P11802 

Entrez Gene ID

1019 

Product Description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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