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Caspase-1 Rabbit Monoclonal Antibody
Catalog #£ºEAB21521
  SKU-Pack Size Availability Size Price
EAB21521-100UL In Stock 100ul €297.70
EAB21521-200UL In Stock 200ul €479.70
If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com
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OlaSciences Phone£º+33 (0) 9 77 4001 556
87, rue des Suisses 65000 Nanterre, E-mail£ºola@olasciences.com
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Product Information
Applications WB, IHC-P, FC
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000¡¡
IHC-P=1:50-200¡¡¡¡
FC=1:10-100
MW (kDa) 45
Conjugate Unconjugate
Specificity Caspase-1 Rabbit Monoclonal Antibody detects endogenous levels of Caspase-1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) CASP1; ICE; IL1BC; IL1BCE; P45
Gene Aliases CASP1
UniProt ID

P29466

Entrez Gene ID

834

Product Description

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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