SKU-Pack Size | Availability | Size | Price | |
EAB10617-30UL | In Stock | 30ul | £119.90 | |
EAB10617-100UL | In Stock | 100ul | £251.90 | |
EAB10617-200UL | In Stock | 200ul | £405.90 |
Please select the country you are in to find your local distributor. |
CUlabSciences | Phone:+44 (0) 1232 330008 | |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | WB, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 49 |
Conjugate | Unconjugate |
Specificity | Phospho-RUNX1/AML1 (Ser249) Rabbit Polyclonal Antibody detects endogenous levels of RUNX1/AML1 protein only when phosphorylated on Ser249. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | AML1; AML1-EVI-1; AMLCR1; CBF-alpha-2; CBF2alpha; CBFA2; EVI-1; Pebp2a2; PEBP2aB; PEBP2alpha; Pebpa2b; RUNX1 |
Gene Aliases | RUNX1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on Jurkat cells, using Phospho-RUNX1/AML1 (Ser249) Rabbit Polyclonal Antibody (EAB10617) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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Specific Protocols | |