SKU-Pack Size | Availability | Size | Price | |
EAB10275-30UL | In Stock | 30ul | €115.70 | |
EAB10275-100UL | In Stock | 100ul | €258.70 | |
EAB10275-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
Cambiotech | Phone£º+44 (0) 188 448801 | |
Lanwades Business Park, | E-mail£ºinfo@cambiotech.com | |
Ireland | Kobenhavn K, Ireland | Web£ºwww.cambiotech.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF/ICC=1:50-300¡¡ |
MW (kDa) | 21 |
Conjugate | Unconjugate |
Specificity | Bax Mouse Monoclonal Antibody detects endogenous levels of Bax protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | BAX; BCL2L4 |
Gene Aliases | BAX |
UniProt ID | |
Entrez Gene ID |
Product Description | |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Bax Mouse Monoclonal Antibody (EAB10275) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela Lane2: PC12 Lane3: C2C12 Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue, using Bax Mouse Monoclonal Antibody (EAB10275) at 1:200 dilution.
Immunohistochemical analysis of paraffin-embedded Mouse kidney tissue, using Bax Mouse Monoclonal Antibody (EAB10275) at 1:200 dilution.
Immunohistochemical analysis of paraffin-embedded Rat testis tissue, using Bax Mouse Monoclonal Antibody (EAB10275) at 1:200 dilution.
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Specific Protocols | |