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Clozapine N-oxide (CAS: 34233-69-7)
Catalog #£ºEBC51077
  SKU-Pack Size Availability Size Price
EBC51077-1ML In Stock 1mL(10mM in DMSO) €89.70
EBC51077-2MG In Stock 2mg €63.70
EBC51077-5MG In Stock 5mg €89.70
EBC51077-10MG In Stock 10mg €128.70
EBC51077-25MG In Stock 25mg €284.70
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Product Information
Synonym(s) Clozapine (N-oxide), MZA8BK588J, N-Oxyclozapine
Chemical Name 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
Application Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration
CAS Number 34233-69-7
Purity ¡Ý99.0%
Molecular Weight 342.82
Molecular Formula C₁₈H₁₉ClN₄O
SMILES CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2O)C=C(C=C4)Cl
Target & IC50 DREADDs
Solubility DMSO: 68 mg/mL (198.35 mM)
Ethanol: 8 mg/mL (23.34 mM)
H₂O: 68 mg/mL (198.35 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.9170 ml 14.5849 ml 29.1698 ml
5 mM 0.5834 ml 2.9170 ml 5.8340 ml
10 mM 0.2917 ml 1.4585 ml 2.9170 ml
50 mM 0.0583 ml 0.2917 ml 0.5834 ml
Shipping Gel Pack
Storage Store at -20¡ãC
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Clozapine N-oxide is a normally biologically inactive metabolite of clozapine that can be used to specifically activate DREAD receptors, engineered G-protein coupled receptors which are activated by otherwise inert drug-like small molecules. Clozapine is metabolized in the liver by the cytochrome P450 system and is a partial agonist of the serotonin receptor.

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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