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Stattic (CAS: 19983-44-9)
Catalog #£ºEBC51124
  SKU-Pack Size Availability Size Price
EBC51124-1ML In Stock 1mL(10mM in DMSO) €63.70
EBC51124-10MG In Stock 10mg €63.70
EBC51124-25MG In Stock 25mg €102.70
EBC51124-50MG In Stock 50mg €180.70
EBC51124-100MG In Stock 100mg €232.70
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Product Information
Synonym(s) STAT3 inhibitor
Chemical Name 6-Nitrobenzo[b]thiophene-1,1-dioxide
Application Stat3 inhibitor V, stattic is an inhibitor of Stat3 activation
CAS Number 19983-44-9
Purity ¡Ý99.0%
Molecular Weight 211.19
Molecular Formula C₈H₅NO₄S
SMILES C1=CC(=CC2=C1C=CS2(=O)=O)[N+](=O)[O-]
Target & IC50 STAT3: IC50 = 5.1¦ÌM
Solubility DMSO: 42 mg/mL (198.87 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 4.7351 ml 23.6754 ml 47.3507 ml
5 mM 0.9470 ml 4.7351 ml 9.4701 ml
10 mM 0.4735 ml 2.3675 ml 4.7351 ml
50 mM 0.0947 ml 0.4735 ml 0.9470 ml
Shipping Gel Pack
Storage Store at -20¡ãC
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

 Stat3 Inhibitor V, Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events. Stattic has been used as a tool for probing the upstream activation of this factor, significantly expressed in many cancer cell lines, and interruption of this pathway in breast cancer cell lines lead to an increased apoptotic rate in these cells. Stat3 Inhibitor V, Stattic is an inhibitor of Stat3.

 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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