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GW 9662 (CAS: 22978-25-2)
Catalog #£ºEBC51105
  SKU-Pack Size Availability Size Price
EBC51105-1ML In Stock 1mL(10mM in DMSO) €63.70
EBC51105-5MG In Stock 5mg €63.70
EBC51105-10MG In Stock 10mg €102.70
EBC51105-25MG In Stock 25mg €154.70
EBC51105-50MG In Stock 50mg €258.70
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Product Information
Synonym(s) 2-Chloro-5-nitrobenzanilide, GW9662, GW-9662, PPAR¦Ã antagonist
Chemical Name 2-chloro-5-nitro-N-phenylbenzamide
Application GW9662 is a specific PPAR¦Ã antagonist
CAS Number 22978-25-2
Purity ¡Ý98.0%
Molecular Weight 276.68
Molecular Formula C₁₃H₉ClN₂O₃
SMILES C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl
Target & IC50 PPAR¦Ã: IC50 = 3.3 nM
PPAR¦Á: IC50 = 32 nM
PPAR¦Ä: IC50 = 2.0 ¦ÌM
Solubility DMSO: 27.7 mg/mL (100 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.6143 ml 18.0714 ml 36.1428 ml
5 mM 0.7229 ml 3.6143 ml 7.2286 ml
10 mM 0.3614 ml 1.8071 ml 3.6143 ml
50 mM 0.0723 ml 0.3614 ml 0.7229 ml
Shipping Gel Pack
Storage Store at -20¡ãC
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

GW 9662 is a selective, irreversible, and effective PPARγ antagonist that also acts as a FXR and PXR agonist. GW 9662 is an irreversible selective antagonist of PPARgamma, which regulates fatty acid storage and glucose metabolism. It is a more potent alternative to the BADGE molecule and is reported to have anticancer properties and to be useful in blocking the differentiation of monocytes to osteoclasts.  

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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