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EHNA hydrochloride (CAS: 51350-19-7)
Catalog #:EBC51094
  SKU-Pack Size Availability Size Price
EBC51094-5MG 2-4 Weeks 5mg £75.90
EBC51094-25MG 2-4 Weeks 25mg £251.90
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Product Information
Synonym(s) NSC263164, EHNA HCl
Chemical Name (2R,3S)-3-(6-Aminopurin-9-yl)nonan-2-ol hydrochloride
Application EHNA hydrochloride is a potent adenosine deaminase and phosphodiesterase type 2 inhibitor
CAS Number 58337-38-5
Purity ≥98%
Molecular Weight 313.8
Molecular Formula C₁₄H₂₃N₅O·HCl
SMILES CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C1N=CN=C2N.Cl
Target & IC50 PDE II: IC50 = 0.8 μM
PDE I/II/IV isozymes: IC50 ≥100 μM
Solubility DMSO : 100 mg/mL (318.64 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.1864 ml 15.9322 ml 31.8644 ml
5 mM 0.6373 ml 3.1864 ml 6.3729 ml
10 mM 0.3186 ml 1.5932 ml 3.1864 ml
50 mM 0.0637 ml 0.3186 ml 0.6373 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

EHNA acts as an inhibitor of adenosine deaminase (ADA) and as a selective inhibitor of cyclic nucleotide phosphodiesterase- 2 (PDE2). EHNA has been used to investigate the protective response of adenosine in myocardial cell studies in vitro, and to understand the role that the adenosine pathway plays in heart studies. Urinary bladder studies in vitro show that EHNA blocks the ATPase and motor activities of cytoplasmic dynein in vitro and cardiac myocyte studies show EHNA to block the activity of cGMP-stimulated phosphodiesterase. 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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