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Dimethyloxaloylglycine (CAS: 89464-63-1)
Catalog #£ºEBC51087
  SKU-Pack Size Availability Size Price
EBC51087-1ML In Stock 1mL(10mM in DMSO) €115.70
EBC51087-10MG In Stock 10mg €63.70
EBC51087-50MG In Stock 50mg €102.70
EBC51087-100MG In Stock 100mg €141.70
EBC51087-250MG In Stock 250mg €284.70
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Product Information
Synonym(s) DMOG, Dimethyloxallyl glycine, N-(methoxyoxoacetyl)-glycine methyl ester
Chemical Name N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Application Dimethyloxaloylglycine is an antagonist of the ¦Á-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase
CAS Number 89464-63-1
Purity ¡Ý99%
Molecular Weight 175.14
Molecular Formula C₆H₉NO₅
SMILES COC(=O)CNC(=O)C(=O)OC
Target & IC50 prolyl-4-hydroxylase: IC50 = 5.18 ¦ÌM
Solubility DMSO: 17.5 mg/mL (100 mM)
Ethanol: 35 mg/mL (199.84 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 5.7097 ml 28.5486 ml 57.0972 ml
5 mM 1.1419 ml 5.7097 ml 11.4194 ml
10 mM 0.5710 ml 2.8549 ml 5.7097 ml
50 mM 0.1142 ml 0.5710 ml 1.1419 ml
Shipping Gel Pack
Storage Store at -20¡ãC
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Dimethyloxaloylglycine is a cell permeable Prolyl 4-hydroxylase (P4H) inhibitor which activates the hypoxia-inducible factor (HIF) in cultured cells. DMOG is reported to delay neuronal cell death caused by trophic factor deprivation through a HIF-1 alpha-independent, glucose-dependent mechanism. 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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