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Z-DEVD-FMK (CAS: 210344-95-9)
Catalog #:EBC51066
  SKU-Pack Size Availability Size Price
EBC51066-1ML In Stock 1mL(10mM in DMSO) £449.90
EBC51066-1MG In Stock 1mg £108.90
EBC51066-5MG In Stock 5mg £306.90
EBC51066-10MG In Stock 10mg £438.90
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Product Information
Synonym(s) Z-D(OMe)E(OMe)VD(OMe)-FMK
Chemical Name Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK
Application Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor
CAS Number 210344-95-9
Purity ≥98.0%
Molecular Weight 668.66
Molecular Formula C₃₀H₄₁FN₄O₁₂
SMILES FCC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(C)C
Target & IC50 caspase-3
Solubility DMSO: 93 mg/mL (139.1 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 1.4955 ml 7.4776 ml 14.9553 ml
5 mM 0.2991 ml 1.4955 ml 2.9911 ml
10 mM 0.1496 ml 0.7478 ml 1.4955 ml
50 mM 0.0299 ml 0.1496 ml 0.2991 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Z-DEVD-FMK is a cell-permeable, irreversible inhibitor of Caspase-3/CPP32. Z-DEVD-FMK is also an irreversible inhibitor of Caspase-6, Caspase-7, caspase-8, and Caspase-10. Z-DEVD-FMK has been shown to inhibit tumor cell apoptosis.

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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