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NBQX disodium salt (CAS: 479347-86-9)
Catalog #:EBC51141
  SKU-Pack Size Availability Size Price
EBC51141-5MG In Stock 5mg £119.90
EBC51141-10MG In Stock 10mg £218.90
EBC51141-25MG In Stock 25mg £438.90
EBC51141-50MG In Stock 50mg £768.90
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Product Information
Synonym(s) AMPA/kainate antagonist
Chemical Name sodium 6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-bis(olate)
Application NBQX disodium salt is a selective and potent AMPA- and kainate-sensitive glutamate receptor antagonist.
CAS Number 479347-86-9
Purity ≥98.0%
Molecular Weight 380.24
Molecular Formula C₁₂H₆N₄O₆SNa₂
SMILES C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])N=C(C(=N3)[O-])[O-].[Na+].[Na+]
Target & IC50 PABP: IC50 >66 μM
Solubility DMSO: 20 mg/ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

NBQX disodium salt is a water soluble, selective, and competitive AMPA/kainate receptor antagonist. Highly potent, NBQX disodium salt works against AMPA and kainate receptors at micromolar concentrations. NBQX disodium salt serves as a neuroprotective agent and anticonvulsant. In vivo, NBQX disodium salt has proven to be active. Kinetic studies involving N-methyl-D-aspartate receptors have used NBQX disodium salt. NBQX disodium salt is analogous to the quinoxalinedione antagonists to the non-NMDA glutamate receptor. In rat neocortex slices, NBQX disodium salt was reported to block excitatory actions. 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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