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Calcitriol (CAS: 32222-06-3)
Catalog #£ºEBC51071
  SKU-Pack Size Availability Size Price
EBC51071-1ML In Stock 1mL(10mM in DMSO) €414.70
EBC51071-2MG In Stock 2mg €141.70
EBC51071-5MG In Stock 5mg €232.70
EBC51071-10MG In Stock 10mg €388.70
EBC51071-25MG In Stock 25mg €778.70
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Product Information
Synonym(s) RO215535, Topitriol, Rocaltrol, Calcijex, 1,25-Dihydroxyvitamin D3
Chemical Name (1¦Á,3¦Â,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
Application Calcitriol is the physiologically active form of vitamin D
CAS Number 32222-06-3
Purity ¡Ý99.0%
Molecular Weight 416.64
Molecular Formula C₂₇H₄₄O₃
SMILES CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
Target & IC50 PBMC: IC50 = 0.03 nM
VDR: IC50 = 0.7 nM
Solubility DMSO: 83 mg/mL (199.21 mM)
Ethanol: 83 mg/mL (199.21 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.4002 ml 12.0008 ml 24.0015 ml
5 mM 0.4800 ml 2.4002 ml 4.8003 ml
10 mM 0.2400 ml 1.2001 ml 2.4002 ml
50 mM 0.0480 ml 0.2400 ml 0.4800 ml
Shipping Gel Pack
Storage Store at -20¡ãC
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Calcitriol is the hormonally active metabolite of vitamin D with the addition of three hydroxyl groups. Its main biological effect is to increase the mineralization of bone and the uptake of calcium from the gut into the blood. Calcitriol activates osteoclasts by causing osteoblasts to release Receptor activator of nuclear factor kappa-B ligand (RANKL). It is also reported to exhibit antitumor properties by inhibiting the proliferation of a variety of carcinomas and leukemia cells.

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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