USA:(540) 808-3925
China:400-117-0038
Canada
Shopping Cart
Sign in \ Register
25-Hydroxycholesterol (CAS: 2140-46-7)
Catalog #:EBC51049
  SKU-Pack Size Availability Size Price
EBC51049-1ML In Stock 1mL(10mM in DMSO) $103.50
EBC51049-5MG In Stock 5mg $88.50
EBC51049-10MG In Stock 10mg $118.50
EBC51049-25MG In Stock 25mg $208.50
EBC51049-50MG In Stock 50mg $343.50
If you want to get a larger packsize, Please contact your local distributor or
email us atinfo@ebiocell.com
Please Select The Country You Are In To Find Your Local Distributor.
EbioCell Phone:(540) 808-3925
Imperial Business Park 4819 Emperor Boulevard, E-mail:order@ebiocell.com
Canada Suite 408 Durham, NC 27703, USA Web:www.ebiocell.com
Product Information
Synonym(s) 25-hydroxycholesterol, (3beta)-isomer, 5-cholestene-3beta,25-diol
Chemical Name cholest-5-ene-3β,25-diol
Application 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells
CAS Number 2140-46-7
Purity ≥99.0%
Molecular Weight 402.65
Molecular Formula C₂₇H₄₆O₂
SMILES CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Target & IC50 HMG-CoA Reductase
Solubility Ethanol: 20 mg/mL
Chloroform: 50 mg/mL
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.4835 ml 12.4177 ml 24.8355 ml
5 mM 0.4967 ml 2.4835 ml 4.9671 ml
10 mM 0.2484 ml 1.2418 ml 2.4836 ml
50 mM 0.0497 ml 0.2484 ml 0.4967 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

25-hydroxy Cholesterol is a dietary cholesterol derivative with a side chain substituted oxysterol that is capable of triggering the activation of many cholesterol molecules. It has been reported to activate ABCA1 signaling, atherosclerosis modulation, and induces apoptosis in human cell lines through caspases activation and bcl-2 downregulation. 25-hydroxy Cholesterol is immunomodulating and is capable of suppressing macrophage differentiation from monocytes.

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Copyright 2015 EbioCell, Inc. All Rights Reserved.  备案号:津ICP备2022005142号-1