Protein Inhibitors - EHNA hydrochloride (CAS: 51350-19-7)

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EHNA hydrochloride (CAS: 51350-19-7)

Catalog #：EBC51094

EHNA hydrochloride
(CAS: 51350-19-7)

SKU-Pack Size	Availability	Size	Price
EBC51094-5MG	2-4 Weeks	5mg	€89.70
EBC51094-25MG	2-4 Weeks	25mg	€297.70

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Product Information

Synonym(s)

NSC263164, EHNA HCl

Chemical Name

(2R,3S)-3-(6-Aminopurin-9-yl)nonan-2-ol hydrochloride

Application

EHNA hydrochloride is a potent adenosine deaminase and phosphodiesterase type 2 inhibitor

CAS Number

58337-38-5

Purity

≥98%

Molecular Weight

313.8

Molecular Formula

C₁₄H₂₃N₅O·HCl

SMILES

CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C1N=CN=C2N.Cl

Target & IC50

PDE II: IC50 = 0.8 μM
PDE I/II/IV isozymes: IC50 ≥100 μM

Solubility

DMSO : 100 mg/mL (318.64 mM)

Preparing Stock Solutions

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	3.1864 ml	15.9322 ml	31.8644 ml
5 mM	0.6373 ml	3.1864 ml	6.3729 ml
10 mM	0.3186 ml	1.5932 ml	3.1864 ml
50 mM	0.0637 ml	0.3186 ml	0.6373 ml

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description

EHNA acts as an inhibitor of adenosine deaminase (ADA) and as a selective inhibitor of cyclic nucleotide phosphodiesterase- 2 (PDE2). EHNA has been used to investigate the protective response of adenosine in myocardial cell studies in vitro, and to understand the role that the adenosine pathway plays in heart studies. Urinary bladder studies in vitro show that EHNA blocks the ATPase and motor activities of cytoplasmic dynein in vitro and cardiac myocyte studies show EHNA to block the activity of cGMP-stimulated phosphodiesterase.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol