USA：(540) 808-3925
China：400-117-0038
Order@ebiocell.com
China
Shopping Cart
Sign in \ Register
Hot Search：
Location：Home > Biochemicals > Protein Inhibitors
Dimethyloxaloylglycine (CAS: 89464-63-1)
Catalog #：EBC51087
  SKU-Pack Size Availability Size Price
EBC51087-1ML In Stock 1mL(10mM in DMSO) ￥890.00
EBC51087-10MG In Stock 10mg ￥490.00
EBC51087-50MG In Stock 50mg ￥790.00
EBC51087-100MG In Stock 100mg ￥1090.00
EBC51087-250MG In Stock 250mg ￥2190.00
If you want to get a larger packsize, Please contact your local distributor or
email us atinfo@ebiocell.com
Please Select The Country You Are In To Find Your Local Distributor.
北京美瑞克生物科技有限公司 Phone：  +86 010-62890160 / 13691184142(微信同号)
2 / F, 128 malianwa North Road, Haidian District, E-mail：   mrkbio@163.com 
China Beijing China Website： www.mrkbio.com
Product Information
Synonym(s) DMOG, Dimethyloxallyl glycine, N-(methoxyoxoacetyl)-glycine methyl ester
Chemical Name N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Application Dimethyloxaloylglycine is an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase
CAS Number 89464-63-1
Purity ≥99%
Molecular Weight 175.14
Molecular Formula C₆H₉NO₅
SMILES COC(=O)CNC(=O)C(=O)OC
Target & IC50 prolyl-4-hydroxylase: IC50 = 5.18 μM
Solubility DMSO: 17.5 mg/mL (100 mM)
Ethanol: 35 mg/mL (199.84 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 5.7097 ml 28.5486 ml 57.0972 ml
5 mM 1.1419 ml 5.7097 ml 11.4194 ml
10 mM 0.5710 ml 2.8549 ml 5.7097 ml
50 mM 0.1142 ml 0.5710 ml 1.1419 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Dimethyloxaloylglycine is a cell permeable Prolyl 4-hydroxylase (P4H) inhibitor which activates the hypoxia-inducible factor (HIF) in cultured cells. DMOG is reported to delay neuronal cell death caused by trophic factor deprivation through a HIF-1 alpha-independent, glucose-dependent mechanism. 
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Antibodies
Primary Antibodies
Monoclonal Antibodies
Polyclonal Antibodies
Recombinant Antibodies
Secondary Antibodies
Antibody Panels
Biochemicals
Antibiotics
Protein Agonists, Antagonists and Activators
Protein Inhibitors
Protein Substrates
Stains, Dyes and Fluorescent Reagents
Other Biochemicals
Support Products
Cell Culture Related Agents
Specialty Cell Culture Media
Primary Cell Culture Media
Basal Cell Culture Media
Contact Us
Phone：919-816-2261
Fax：1-886-598-2438
Email：ebiocell@ebiocell.com
Address： Commercial Park West 2327 Englert Dr.
Room 101-5 Durham ,NC 27713
Copyright 2015 EbioCell, Inc. All Rights Reserved. 　备案号：津ICP备2022005142号-1