Protein Inhibitors - Z-DEVD-FMK (CAS: 210344-95-9)

Z-DEVD-FMK (CAS: 210344-95-9)

Catalog #：EBC51066

Z-DEVD-FMK (CAS: 210344-95-9)

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Product Information

Synonym(s)

Z-D(OMe)E(OMe)VD(OMe)-FMK

Chemical Name

Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK

Application

Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor

CAS Number

210344-95-9

Purity

≥98.0%

Molecular Weight

668.66

Molecular Formula

C₃₀H₄₁FN₄O₁₂

SMILES

FCC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(C)C

Target & IC50

caspase-3

Solubility

DMSO: 93 mg/mL (139.1 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Z-DEVD-FMK is a cell-permeable, irreversible inhibitor of Caspase-3/CPP32. Z-DEVD-FMK is also an irreversible inhibitor of Caspase-6, Caspase-7, caspase-8, and Caspase-10. Z-DEVD-FMK has been shown to inhibit tumor cell apoptosis.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol