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|WB, IHC-P, IF/ICC
|Human, Mouse, Rat, Monkey, Dog, Pig, Bovine, Chicken, Hamster, Sheep
|Host / Isotype
|GAPDH Rabbit Polyclonal Antibody detects endogenous levels of GAPDH protein.
|In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
|Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
|For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|Glyceraldehyde-3-phosphate dehydrogenase; GAPDH
|Entrez Gene ID
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.
|Product Image Gallery
Western blot analysis of extracts on different cells, using GAPDH Rabbit Polyclonal Antibody (EAB10004) at 1:20000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane4: Rat brain
Lane5: Mouse brain