Polyclonal Antibodies - TKT/Transketolase Rabbit Polyclonal Antibody

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TKT/Transketolase Rabbit Polyclonal Antibody

Catalog #：EAB14039

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14039-100UL	In Stock	100ul	$343.50
EAB14039-200UL	In Stock	200ul	$553.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300 IF/ICC=1:50-300
MW (kDa)	68
Conjugate	Unconjugate
Specificity	TKT/Transketolase Rabbit Polyclonal Antibody detects endogenous levels of TKT/Transketolase protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	TKT; HEL-S-48; HEL107; SDDHD; TK; TKT1; transketolase
Gene Aliases	TKT
UniProt ID	P29401
Entrez Gene ID	7086

Product Description

Transketolase (TKT) is a homodimer in the pentose phosphate pathway (PPP) that catalyzes the interketol transfer between ketoses and aldoses. This enzyme, along with transaldolase, connects the nonoxidative branch of the PPP with glycolysis. Several regions of TKT are evolutionarily conserved from gram-negative bacteria to mammals. There is evidence that hypoxic and non-hypoxic induction of HIF1-α increases the expression of TKT. Because cancer cells rely on TKT in altered cell metabolism for nucleic acid synthesis, work has been done to develop inhibitors of TKT as novel cancer treatments.

Product Image Gallery
Western blot analysis of extracts on different cells, using TKT/Transketolase Rabbit Polyclonal Antibody (EAB14039) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Lane1: MCF7 Lane2: HepG2 Lane3: Mouse liver

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol