SKU-Pack Size | Availability | Size | Price | |
EAB22134-100UL | In Stock | 100ul | ¥2290.00 | |
EAB22134-200UL | In Stock | 200ul | ¥3690.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IP, IHC-P, IF/ICC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 |
MW (kDa) | 31 |
Conjugate | Unconjugate |
Specificity | MTAP Rabbit Monoclonal Antibody detects endogenous levels of MTAP protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | MTAPase; BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249 |
Gene Aliases | MTAP |
UniProt ID | |
Entrez Gene ID |
Product Description | |
MTAP (also designated MSAP) catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP maps to human chromosome 9p21 and is linked to the tumor suppressor gene, p16INK4A (2,3). Deficient levels of MTAP can occur in cancers primarily through codeletion of the MTAP gene and the p16INK4A gene (4-6). Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using MTAP Rabbit Monoclonal Antibody (EAB22134) at 1:500 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: HT29 Lane2: Mouse kidney |
Specific Protocols | |