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|Applications||WB, IHC-P, IF/ICC, FC|
|Species Reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit IgG|
|Specificity||Rad18 Rabbit Monoclonal Antibody detects endogenous levels of Rad18 protein.|
|Formulation||In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.|
|Storage||Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.|
|Research Use||For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.|
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|Synonym(s)||hHR18; hRAD18; RNF73; mRAD18Sc; RAD18; Rad18sc|
|Entrez Gene ID|
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
|Product Image Gallery|
Western blot analysis of extracts on different cells, using Rad18 Rabbit Monoclonal Antibody (EAB21702) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.