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Location：Home > Antibodies > Primary Antibodies > Recombinant Antibodies
Phospho-PKR (Thr446) Rabbit Monoclonal Antibody
Catalog #：EAB21661
Datasheet
  SKU-Pack Size Availability Size Price
EAB21661-100UL In Stock 100ul ￥2590.00
If you want to get a larger packsize, Please contact your local distributor or
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北京美瑞克生物科技有限公司 Phone：  +86 010-62890160 / 13691184142(微信同号)
2 / F, 128 malianwa North Road, Haidian District, E-mail：   mrkbio@163.com 
China Beijing China Website： www.mrkbio.com
Product Information
Applications WB, IP, IHC-P
Species Reactivity Human
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000　
IP=1:10-100　
IHC-P=1:50-200
MW (kDa) 62
Conjugate Unconjugate
Specificity Phospho-PKR (Thr446) Rabbit Monoclonal Antibody detects endogenous levels of PKR only when phosphorylated at Thr446.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
Product Bioinformatics
Synonym(s) PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83; EIF2AK2; Tik
Gene Aliases EIF2AK2
UniProt ID

P19525
Entrez Gene ID

5610
Product Description

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. 
Product Image Gallery
Western blot analysis of extracts on Hela cells treated with TNFalpha, using Phospho-PKR (Thr446) Rabbit Monoclonal Antibody (EAB21661) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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