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|WB, IHC-P, IF, ELISA
|Human, Mouse, Rat
|Host / Isotype
|TRβ1 Rabbit Polyclonal Antibody detects endogenous levels of TRβ1 protein.
|In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
|Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
|For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|THRB; ERBA2; NR1A2; THR1; Thyroid hormone receptor beta
|Entrez Gene ID
TRβ1 (also designated TR beta 1, THRB, THB) is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
|Product Image Gallery
Western blot analysis of extracts on different cells, using TRβ1 Rabbit Polyclonal Antibody (EAB14044) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.