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|北京美瑞克生物科技有限公司||Phone： +86 010-62890160 / 13691184142(微信同号)|
|2 / F, 128 malianwa North Road, Haidian District,||E-mail： email@example.com|
|China||Beijing China||Website： www.mrkbio.com|
|Applications||WB, IHC-P, IF/ICC, ELISA|
|Species Reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit IgG|
|Specificity||TIMP2 Rabbit Polyclonal Antibody detects endogenous levels of TIMP2 protein.|
|Formulation||In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.|
|Storage||Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.|
|Research Use||For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.|
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|Synonym(s)||TIMP2; Metalloproteinase inhibitor 2; CSC-21K; Tissue inhibitor of metalloproteinases 2; TIMP-2|
|Entrez Gene ID|
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
|Product Image Gallery|
Western blot analysis of extracts on A549 cells, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Immunohistochemical analysis of paraffin-embedded Human colon tissue, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:200 dilution.
Immunohistochemical analysis of paraffin-embedded Human kidney tissue, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:200 dilution.
Immunofluorescence analysis of A549 cell, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:200 dilution.