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|WB, IHC-P, IF/ICC
|Human, Mouse, Rat
|Host / Isotype
|TIA1 Rabbit Polyclonal Antibody detects endogenous levels of TIA1 protein.
|In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
|Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
|For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|WDM; ALS26; mTIA-1; p40-TIA-1; RNA binding protein TIA 1; TIA1
|Entrez Gene ID
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.
|Product Image Gallery
Western blot analysis of extracts on BT474 cells, using TIA1 Rabbit Polyclonal Antibody (EAB14040) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 42 kDa; Observed band size: 54 kDa
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using TIA1 Rabbit Polyclonal Antibody (EAB14040) at 1:100 dilution.