SKU-Pack Size | Availability | Size | Price | |
EAB10445-30UL | In Stock | 30ul | ¥1090.00 | |
EAB10445-100UL | In Stock | 100ul | ¥2290.00 | |
EAB10445-200UL | In Stock | 200ul | ¥3690.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 |
MW (kDa) | 83 |
Conjugate | Unconjugate |
Specificity | Phospho-PKCε (Ser729) Rabbit Polyclonal Antibody detects endogenous levels of PKCε only when phosphorylated at Ser729. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | nPKC-epsilon; PKC[e]; PKCE; Pkcea; PKCepsilon; PRKCE; R75156 |
Gene Aliases | PRKCE |
UniProt ID | |
Entrez Gene ID |
Product Description | |
PKCε (also designated PKC epsilon, PRKCE, or PKCE) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. |
Product Image Gallery | |
Western blot analysis of extracts on Hela cells treated with PMA, using Phospho-PKCε (Ser729) Rabbit Polyclonal Antibody (EAB10445) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue, using Phospho-PKCε (Ser729) Rabbit Polyclonal Antibody (EAB10445) at 1:200 dilution.
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Specific Protocols | |