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|北京美瑞克生物科技有限公司||Phone： +86 010-62890160 / 13691184142(微信同号)|
|2 / F, 128 malianwa North Road, Haidian District,||E-mail： email@example.com|
|China||Beijing China||Website： www.mrkbio.com|
|Species Reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse IgG1|
|Specificity||Erk5 Mouse Monoclonal Antibody detects endogenous levels of Erk5 protein.|
|Formulation||In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.|
|Storage||Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.|
|Research Use||For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.|
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
|Synonym(s)||BMK-1; BMK1; ERK-5; ERK4; ERK5; Erk5-T; MAPK7; PRKM7|
|Entrez Gene ID|
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
|Product Image Gallery|
Western blot analysis of extracts on different cells, using Erk5 Mouse Monoclonal Antibody (EAB14603) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 89 kDa; Observed band size: 115 kDa
Immunohistochemical analysis of paraffin-embedded Human kidney tissue, using Erk5 Mouse Monoclonal Antibody (EAB14603) at 1:200 dilution.