This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
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Western blot analysis of extracts on different cells, using 14-3-3 eta Mouse Monoclonal Antibody (EAB13301) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Lane1: Hela Lane2: Rat brain
Immunohistochemical analysis of paraffin-embedded Human colon carcinoma tissue, using 14-3-3 eta Mouse Monoclonal Antibody (EAB13301) at 1:200 dilution.