This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
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Western blot analysis of extracts on Hela, 293T, NIH/3T3, Mouse Liver, Rat Liver, Rat Kidney cells, using Cytochrome C Mouse Monoclonal Antibody (EAB14622) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Immunohistochemical analysis of paraffin-embedded Human Breast caricnoma tissue, using Cytochrome C Mouse Monoclonal Antibody (EAB14622) at 1:500 dilution.