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IWP-3 (CAS: 687561-60-0)
Catalog #:EBC51121
  SKU-Pack Size Availability Size Price
EBC51121-5MG In Stock 5mg ¥990.00
EBC51121-10MG In Stock 10mg ¥1590.00
EBC51121-25MG In Stock 25mg ¥3290.00
EBC51121-50MG In Stock 50mg ¥4990.00
EBC51121-100MG In Stock 100mg ¥7990.00
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Product Information
Synonym(s) Inhibitor of Wnt Production-3, IWP3, IWP 3
Chemical Name 2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N-(6-methyl-2-benzothiazolyl)-acetamide
Application IWP-3 is an inhibitor of Wnt production
CAS Number 687561-60-0
Purity ≥98.0%
Molecular Weight 484.59
Molecular Formula C₂₂H₁₇FN₄O₂S₃
SMILES O=C(NC1=NC2=CC=C(C)C=C2S1)CSC3=NC(CCS4)=C4C(N3C5=CC=C(F)C=C5)=O
Target & IC50 Wnt: IC50 = 40 nM
Solubility DMSO: 2 mg/ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

IWP-3 is a Wnt pathway inhibitor by inactivating the Porcupine O-acyltransferase which palmitoylates Wnt proteins. It is reported to inhibit embryonic stem cell self-renewal and promote cardiomyocyte differentiation from human stem cells. 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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