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SU 5402 (CAS: 215543-92-3)
Catalog #：EBC51106
SU 5402 (CAS: 215543-92-3)
  SKU-Pack Size Availability Size Price
EBC51106-1ML In Stock 1mL(10mM in DMSO) ￥790.00
EBC51106-5MG In Stock 5mg ￥790.00
EBC51106-10MG In Stock 10mg ￥990.00
EBC51106-25MG In Stock 25mg ￥2190.00
EBC51106-25MG In Stock 50mg ￥3190.00
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Product Information
Synonym(s) SU5402, SU-5402, VEGFR and FGFR inhibitor
Chemical Name 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
Application SU 5402 is a FGFR-specific tyrosine kinase inhibitor
CAS Number 215543-92-3
Purity ≥99.0%
Molecular Weight 296.32
Molecular Formula C₁₇H₁₆N₂O₃
SMILES CC1=CNC(\\C=C2/C(=O)NC3=CC=CC=C23)=C1CCC(O)=O
Target & IC50 VEGFR2: IC50 = 20 nM
FGFR1: IC50 = 30 nM
PDGFRβ: IC50 = 510 nM
Solubility DMSO: 59 mg/mL (199.11 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.3747 ml 16.8737 ml 33.7473 ml
5 mM 0.6749 ml 3.3747 ml 6.7495 ml
10 mM 0.3375 ml 1.6874 ml 3.3747 ml
50 mM 0.0675 ml 0.3375 ml 0.6749 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

SU 5402 is a potent and selective fibroblast growth factor receptor (FGFR) and vascular endothelial growth factor receptor (VEGFR) inhibitor. It is reported to exhibit antitumor properties, attenuates the integrin Beta4-induced differentiation of neural stem cells, and inhibits embryonic left-right determination.  
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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