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SB 202190 (CAS: 152121-30-7)
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Catalog #：EBC51002
Datasheet
SB 202190 (CAS: 152121-30-7)
  SKU-Pack Size Availability Size Price
EBC51002-1ML In Stock 1mL(10mM in DMSO) ￥590.00 / ￥413.00
EBC51002-10MG In Stock 10mg ￥590.00 / ￥413.00
EBC51002-50MG In Stock 50mg ￥1190.00 / ￥833.00
EBC51002-100MG In Stock 100mg ￥1990.00 / ￥1393.00
EBC51002-200MG In Stock 200mg ￥2990.00 / ￥2093.00
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Product Information
Synonym(s) SB-202190, SB202190, FHPI, 4-[4-(4-Fluorphenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
Chemical Name 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole
Application SB 202190 is an inhibitor of the isoforms p38α and p38β
CAS Number 152121-30-7
Purity ≥98%
Molecular Weight 331.34
Molecular Formula C₂₀H₁₄FN₃O
SMILES FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1
Target & IC50 p38α: IC50 = 14.3 nM (human)
p38 MAP kinase: IC50 = 30 nM
p38 β: IC50 = 100 nM
Toxoplasma gondii: IC50 = 1 μM
Solubility DMSO: 33.1 mg/mL (100 mM)
PS: < 1 mg/ml refers to the product slightly soluble or insoluble
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.0180 ml 15.0902 ml 30.1805 ml
5 mM 0.6036 ml 3.0180 ml 6.0361 ml
10 mM 0.3018 ml 1.5090 ml 3.0181 ml
50 mM 0.0604 ml 0.3018 ml 0.6036 ml
Shipping Gel Pack
Storage Store at -20° C
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Product Description

SB 202190 is a selective and potent p38 MAP kinases inhibitor, binding to its ATP pocket. It has negligible inhibiting properties on other MAP kinases such as ERKs and JNKs. SB 202190 is reported to be used to induce cardiomyocyte differentiation from human embryonic stem cells and increase neural stem cell self-renewal.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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