| SKU-Pack Size | Availability | Size | Price | |
| EAB14507-30UL | In Stock | 30ul | $163.50 | |
| EAB14507-100UL | In Stock | 100ul | $343.50 | |
| EAB14507-200UL | In Stock | 200ul | $553.50 |
| Please select the country you are in to find your local distributor. |
| EbioCell | Phone:(540) 808-3925 | |
| Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
| Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
| Product Information | |
| Applications | WB, ELISA |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000 |
| MW (kDa) | 149 |
| Conjugate | Unconjugate |
| Specificity | Phospho-Raptor (Ser863) Rabbit Polyclonal Antibody detects endogenous levels of Raptor protein only when phosphoryated at Ser863. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | Regulatory associated protein of MTOR complex 1; KOG1; Mip1; RPTOR |
| Gene Aliases | RPTOR |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Raptor also known as RPTOR is a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. Rapto plays a pivotal role in the mammalian target of rapamycin (mTOR) signaling pathway, which is crucial for regulating cell growth, proliferation, and survival in response to nutrient availability. Specifically, Raptor acts as a scaffold that facilitates interaction between mTOR and substrates, including 4E-BP1, thereby promoting phosphorylation and activation. This interaction is vital for cellular response to nutrient levels, as Raptor-mTOR complex is sensitive to changes in nutrient status, allowing cells to adapt growth and metabolism accordingly. Under nutrient-rich conditions, Raptor enhances mTOR activity, while in nutrient-deprived states, Raptor serves as a negative regulator, inhibiting mTOR signaling to conserve resources. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on MCF7, Mouse lung cells, using Phospho-Raptor (Ser863) Rabbit Polyclonal Antibody (EAB14507) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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| Specific Protocols | |