USA£º(540) 808-3925
China£º400-117-0038
Spain
Shopping Cart
Sign in \ Register
Phospho-XPA (Ser196) Rabbit Polyclonal Antibody
Catalog #£ºEAB13853
  SKU-Pack Size Availability Size Price
EAB13853-30UL In Stock 30ul €141.70
EAB13853-100UL In Stock 100ul €297.70
EAB13853-200UL In Stock 200ul €479.70
If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com
Please select the country you are in to find your local distributor.
Betaclonal Phone£º+34 (0)91 471 6763
29/1 Lomonosovsky Pr, E-mail£ºtech@betaclonal.com
Spain Madrid, Spain Web£ºwww.betaclonal.com
Product Information
Applications WB, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000
MW (kDa) 31
Conjugate Unconjugate
Specificity Phospho-XPA (Ser196) Rabbit Polyclonal Antibody detects endogenous levels of XPA protein only when phosphorylated at Ser196.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) XP1; XPAC; XPA
Gene Aliases XPA
UniProt ID

P23025

Entrez Gene ID

7507

Product Description

XPA also known as XP1 is a zinc finger protein plays a critical role in the nucleotide excision repair (NER) pathway, which is essential for repairing DNA damage caused by ultraviolet (UV) light. This function is particularly important as deficiencies in NER can lead to xeroderma pigmentosum, a genetic disorder that significantly increases the risk of skin cancer due to the accumulation of unrepaired DNA lesions. XPA is responsible for coordinating the assembly of the preincision complex necessary for recognizing and excising damaged DNA, and XPA exhibits a unique ability to bind to both single-stranded and double-stranded DNA, enhancing efficiency in damage recognition. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Copyright 2015 EbioCell, Inc. All Rights Reserved. ¡¡±¸°¸ºÅ£º½òICP±¸2022005142ºÅ-1