Polyclonal Antibodies - Phospho-LIMK1 (Ser310) Rabbit Polyclonal Antibody

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Phospho-LIMK1 (Ser310) Rabbit Polyclonal Antibody

Catalog #：EAB14521

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14521-30UL	In Stock	30ul	€141.70
EAB14521-100UL	In Stock	100ul	€297.70
EAB14521-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	72
Conjugate	Unconjugate
Specificity	Phospho-LIMK1 (Ser310) Rabbit Polyclonal Antibody detects endogenous levels of LIMK1 only when phosphorylated at Ser310.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	LIM domain kinase 1; Lim kinase 1; LIMK; LIMK-1; KIZ-1; LIMK1
Gene Aliases	LIMK1
UniProt ID	P53667
Entrez Gene ID	3984

Product Description

LIMK1(LIM Kinase 1) is a member of the LIM kinase family. LIMK1 plays a crucial role in regulating the actin cytoskeleton by phosphorylating and inactivating Cofilin, a protein that severs actin filaments. This regulation is vital for maintaining cellular structure and motility, as LIMK1 influences processes such as cell migration, morphogenesis, and neuronal differentiation. LIMK1′s ability to modulate actin dynamics is particularly important in developmental biology and cancer metastasis, where altered cell movement can lead to significant physiological changes. Expression patterns of LIMK1 and LIMK2 suggest distinct roles during development, with LIMK1 being implicated in inhibiting neuronal differentiation in certain contexts.

Product Image Gallery
Western blot analysis of extracts on 293T cells, using Phospho-LIMK1 (Ser310) Rabbit Polyclonal Antibody (EAB14521) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol