Monoclonal Antibodies - TSG101 Mouse Monoclonal Antibody

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TSG101 Mouse Monoclonal Antibody

Catalog #：EAB22873

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22873-100UL	In Stock	100ul	￡284.90

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email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IP, IHC-P, IF/ICC, FC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:5000-20000　 IP=1:100-500 IHC-P=1:500-2000　 IF/ICC=1:500-2000　 FC=1:100-500
MW (kDa)	44
Conjugate	Unconjugate
Specificity	TSG101 Mouse Monoclonal Antibody detects endogenous levels of TSG101 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Tumor susceptibility 101; TSG10; VPS23; TSG101
Gene Aliases	TSG101
UniProt ID	Q99816
Entrez Gene ID	7251

Product Description

TSG101(Tumor susceptibility 101) is a multi-domain cytoplasmic protein and fundamental component of ESCRT complex I, which is intimately involved in regulating the trafficking of proteins throughout the endosomal compartment. TSG101 plays a crucial role in cellular processes as TSG101 is involved in the regulation of the endosomal sorting complex required for transport (ESCRT), which is essential for the degradation of membrane proteins and the regulation of cellular signaling pathways. This function is particularly important in tumor suppression, as proper functioning of the ESCRT machinery can prevent the accumulation of signaling molecules that promote cell proliferation and survival, thereby inhibiting tumorigenesis.

Product Image Gallery
Western blot analysis of extracts on Hela, HEK293, Jurkat, K562 cells, using TSG101 Mouse Monoclonal Antibody (EAB22873) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue, using TSG101 Mouse Monoclonal Antibody (EAB22873) at 1:1000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol