| SKU-Pack Size | Availability | Size | Price | |
| EAB22615-100UL | In Stock | 100ul | €258.70 |
| Please select the country you are in to find your local distributor. |
| Cambiotech | Phone£º+44 (0) 188 448801 | |
| Lanwades Business Park, | E-mail£ºinfo@cambiotech.com | |
| Ireland | Kobenhavn K, Ireland | Web£ºwww.cambiotech.com |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC, ELISA |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:100-500¡¡ IF/ICC=1:100-500 |
| MW (kDa) | 39 |
| Conjugate | Unconjugate |
| Specificity | Islet-1/ISL1 Mouse Monoclonal Antibody detects endogenous levels of Islet-1/ISL1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | ISL LIM homeobox 1; Isl-1; ISLET1; ISL1 |
| Gene Aliases | ISL1 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Islet-1 also konwn as ISL1 is a member of the LIM/homeodomain family of transcription factors. Islet-1 plays a crucial role in pancreatic islets of Langerhans development and is essential for motor neuron differentiation in the neural tube. Islet-1 influences embryonic development and organogenesis, particularly in heart and pancreas, where Islet-1 helps define cardiac progenitor cell populations and is necessary for normal cardiac development and asymmetry. Islet-1 is involved in patterning developing mouse teeth by activating Bmp4 expression in specific areas, demonstrating importance in both developmental biology and potential implications in regenerative medicine. |
| Product Image Gallery | |
![]() Immunohistochemical analysis of paraffin-embedded Mouse kidney tissue, using Islet-1/ISL1 Mouse Monoclonal Antibody (EAB22615) at 1:200 dilution.
![]() Immunohistochemical analysis of paraffin-embedded Rat kidney tissue, using Islet-1/ISL1 Mouse Monoclonal Antibody (EAB22615) at 1:200 dilution.
![]() Immunofluorescence analysis of HEK293 cell, using Islet-1/ISL1 Mouse Monoclonal Antibody (EAB22615) at 1:200 dilution.
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| Specific Protocols | |