Polyclonal Antibodies - Histone H1.0 Rabbit Polyclonal Antibody

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Histone H1.0 Rabbit Polyclonal Antibody

Catalog #：EAB12128

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB12128-30UL	In Stock	30ul	￡97.90
EAB12128-100UL	In Stock	100ul	￡218.90
EAB12128-200UL	In Stock	200ul	￡372.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	21
Conjugate	Unconjugate
Specificity	Histone H1.0 Rabbit Polyclonal Antibody detects endogenous levels of Histone H1.0 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	H1.0 linker histone; Histone H10; H10; H1.0; H1F0; H1FV; H1-0
Gene Aliases	H1-0
UniProt ID	P07305
Entrez Gene ID	3005

Product Description

Histone H1.0 also known as H1F0, H1-0 is a member of the H1 family of linker histones. Histone H1.0 plays a crucial role in chromatin structure and function by interacting with linker DNA between nucleosomes, facilitating DNA compaction into higher-order chromatin. Histone H1.0 is expressed in cells undergoing terminal differentiation or those with low rates of division, distinguishing this protein from other somatic H1 histones typically found in proliferating cells. Histone H10 is derived from the intronless gene H1F0, located on chromosome 22q13.1 in humans, and is widely expressed across various tissues in most vertebrates, highlighting an essential role in cellular processes.

Product Image Gallery
Western blot analysis of extracts on A549 cells, using Histone H1.0 Rabbit Polyclonal Antibody (EAB12128) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 21 kDa; Observed band size: 28 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol