Q7L8A9

VASH1(Vasohibin 1)  also known as TTCP1 plays a crucial role in regulating angiogenesis, which is essential for normal physiological processes such as wound healing and tissue repair, as well as in pathological conditions like cancer. This secreted protein is primarily expressed in endothelial cells, particularly in brain and placental tissues, where VASH1 is involved in a self-regulating feedback mechanism that inhibits angiogenesis in an autocrine manner. By inhibiting endothelial cell proliferation, migration, and network formation, VASH1 serves as a critical endogenous inhibitor that balances effects of pro-angiogenic factors like vascular endothelial growth factor (VEGF) and fibroblast growth factor 2.