| SKU-Pack Size | Availability | Size | Price | |
| EAB22435-30UL | In Stock | 30ul | ¥890.00 | |
| EAB22435-100UL | In Stock | 100ul | ¥1990.00 |
| Please select the country you are in to find your local distributor. |
| 北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
| 2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
| China | Beijing China | Website: www.mrkbio.com |
| Product Information | |
| Applications | WB, IHC-P, IF, ELISA |
| Species Reactivity | Human |
| Host / Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:500-2000 IHC-P=1:100-500 IF=1:50-200 FC=1:50-200 |
| MW (kDa) | 48 |
| Conjugate | Unconjugate |
| Specificity | Cyclin B1 Mouse Monoclonal Antibody detects endogenous levels of Cyclin B1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | Cyclin B1; CCNB; CCNB1 |
| Gene Aliases | CCNB1 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cyclin B1 also known as CCNB1 is a regulatory protein essential for controlling the cell cycle at the G2/M transition, forming a complex with the cyclin-dependent kinase CDK1 to create the maturation-promoting factor (MPF). This complex initiates mitosis in eukaryotic cells, making cyclin B1 crucial for proper cell division. Dysregulation of cyclin B1 can lead to uncontrolled cell proliferation and is associated with various cancers, highlighting cyclin B1′s importance in cell cycle regulation and oncogenesis. Studying cyclin B1′s function provides insights into the mechanisms of cell division and potential therapeutic targets for cancer treatment. Cyclin B1 monoclonal antibody (GNS1) enables researchers to detect and analyze cyclin B1 expression and localization in different tissues and cell types, contributing to a better understanding of cyclin B1′s role in cellular processes. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Hela, Jurkat, K562, PC12 cells, using Cyclin B1 Mouse Monoclonal Antibody (EAB22435) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 48 kDa; Observed band size: 60 kDa ![]() Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue, using Cyclin B1 Mouse Monoclonal Antibody (EAB22435) at 1:200 dilution.
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| Specific Protocols | |