Monoclonal Antibodies - CDK2 Mouse Monoclonal Antibody

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CDK2 Mouse Monoclonal Antibody

Catalog #：EAB21333

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21333-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, IHC-P, IF/ICC, FC, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 IF/ICC=1:100-500　 FC=1:50-200
MW (kDa)	34
Conjugate	Unconjugate
Specificity	CDK2 Mouse Monoclonal Antibody detects endogenous levels of CDK2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Cyclin dependent kinase 2; CDKN2; p33(CDK2); CDK2
Gene Aliases	CDK2
UniProt ID	P24941
Entrez Gene ID	1017

Product Description

CDK2 is a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. Cdk2 plays a fundamental role in cell cycle regulation by partnering with cyclins E and A to control the transition from the G1 phase to the S phase and the progression through the S phase, respectively. These interactions are critical for the initiation of DNA replication and the maintenance of genomic integrity, making Cdk2 essential for proper cell division and preventing uncontrolled cell proliferation. Dysregulation of Cdk2 activity is implicated in various cancers, highlighting Cdk2′s importance as a target for therapeutic intervention and cancer research. The ability of Cdk2 to form complexes with different cyclins allows for precise temporal control of kinase activity, ensuring that cells replicate DNA accurately and divide correctly.

Product Image Gallery
Western blot analysis of extracts on Hela, K562, Jurkat, A431, NIH/3T3 cells, using CDK2 Mouse Monoclonal Antibody (EAB21333) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue, using CDK2 Mouse Monoclonal Antibody (EAB21333) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol