| SKU-Pack Size | Availability | Size | Price | |
| EAB21543-100UL | In Stock | 100ul | $298.50 |
| Please select the country you are in to find your local distributor. |
| EbioCell | Phone:(540) 808-3925 | |
| Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
| Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
| Product Information | |
| Applications | IHC-P, ELISA |
| Species Reactivity | Human |
| Host / Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Applications Dilutions | IHC-P=1:100-500 |
| MW (kDa) | 14 |
| Conjugate | Unconjugate |
| Specificity | α-Synuclein Mouse Monoclonal Antibody detects endogenous levels of α-Synuclein protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | Synuclein alpha; PD1; NACP; PARK1; PARK4; alphaSYN; α Synuclein; SNCA |
| Gene Aliases | SNCA |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
α-synuclein is a pivotal protein primarily expressed in neuronal cell bodies and synapses, where α-synuclein plays a crucial role in synaptic regulation and neuronal plasticity, essential for maintaining proper brain function and facilitating communication between neurons. α-synuclein is deeply involved in synaptic vesicle trafficking and neurotransmitter release, processes vital for efficient neuronal signaling. α-synuclein is implicated in the pathogenesis of several neurodegenerative diseases, including Parkinson′s disease and Alzheimer′s disease, where abnormal aggregation is a hallmark of disease progression. Additionally, α-synuclein expression is modulated during hematopoietic cell differentiation, indicating broader significance in cellular processes beyond the nervous system. |
| Product Image Gallery | |
![]() Immunohistochemical analysis of paraffin-embedded Human brain tissue, using α-Synuclein Mouse Monoclonal Antibody (EAB21543) at 1:200 dilution.
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| Specific Protocols | |