Monoclonal Antibodies - NPM Mouse Monoclonal Antibody

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NPM Mouse Monoclonal Antibody

Catalog #：EAB21981

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21981-100UL	In Stock	100ul	$298.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Monkey
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	33
Conjugate	Unconjugate
Specificity	NPM Mouse Monoclonal Antibody detects endogenous levels of NPM protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Nucleophosmin 1; Nucleophosmin; B23; NPM; NPM1
Gene Aliases	NPM1
UniProt ID	P06748
Entrez Gene ID	4869

Product Description

NPM also known as NPM1, B23 is a multifunctional protein, plays a crucial role in ribosomal assembly and ribosomal RNA transport, essential for protein synthesis in cells. NPM′s nucleolar localization is particularly important for ribosome biogenesis, and disruption in this process can lead to impaired cellular function and contribute to diseases such as cancer. NPM undergoes significant post-translational modifications, including phosphorylation by Cdc2 kinase during mitosis, which regulates activity and protein interactions. NPM′s interaction with various proteins, including karyopherin α and karyopherin β, highlights a role in nuclear transport, making NPM vital for maintaining cellular homeostasis and function.

Product Image Gallery

Western blot analysis of extracts on Hela, HEK293, HepG2 cells, using NPM Mouse Monoclonal Antibody (EAB21981) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Human liver carcinoma tissue, using NPM Mouse Monoclonal Antibody (EAB21981)(green) at 1:200 dilution.

Immunofluorescence analysis of Hela cell, using NPM Mouse Monoclonal Antibody (EAB21981) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol