Monoclonal Antibodies - PDGF Receptor β Mouse Monoclonal Antibody

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PDGF Receptor β Mouse Monoclonal Antibody

Catalog #：EAB22781

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22781-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	124
Conjugate	Unconjugate
Specificity	PDGF Receptor β Mouse Monoclonal Antibody detects endogenous levels of PDGF Receptor β protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Platelet derived growth factor receptor beta; IMF1; KOGS; IBGC4; JTK12; OPDKD; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1; PDGFRB
Gene Aliases	PDGFRB
UniProt ID	P09619
Entrez Gene ID	5159

Product Description

PDGF Receptor β also known as PDGFR beta, PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGF Receptor β plays a crucial role in cell signaling, particularly in the regulation of cell growth, survival, and migration, which are vital processes in tissue repair and development. PDGFR-β is primarily located on the surface of mesenchymal and glial cells, where PDGFR-β mediates the effects of its ligand, PDGF-BB, leading to receptor dimerization and activation of downstream signaling pathways. PDGFR-β′s ability to bind specifically to the B subunit of PDGF is essential for its function, as PDGFR-β triggers a cascade of intracellular events that influence cellular behavior. Dysregulation of PDGFR-β signaling has been implicated in various pathologies, including chronic myelomonocytic leukemia (CMML), highlighting PDGFR-β′s importance as a therapeutic target in cancer treatment.

Product Image Gallery
Western blot analysis of extracts on NIH/3T3 cells, using PDGF Receptor β Mouse Monoclonal Antibody (EAB22781) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol