Monoclonal Antibodies - Smad4 Mouse Monoclonal Antibody

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Smad4 Mouse Monoclonal Antibody

Catalog #：EAB22357

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22357-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, IHC-P, IF/ICC, FC, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 IF/ICC=1:100-500　 FC=1:10-100
MW (kDa)	60
Conjugate	Unconjugate
Specificity	Smad4 Mouse Monoclonal Antibody detects endogenous levels of Smad4 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	SMAD family member 4; JIP; DPC4; MADH4; MYHRS; SMAD4
Gene Aliases	SMAD4
UniProt ID	Q13485
Entrez Gene ID	4089

Product Description

Smad4 also known as DPC4 is a member of the Smad family of signal transduction proteins. Smad4 plays a crucial role as a central mediator in the transforming growth factor-beta (TGFβ) and bone morphogenetic protein (BMP) signaling pathways, which are essential for regulating cellular processes such as proliferation, differentiation, and apoptosis. By interacting with other Smad family members, Smad4 facilitates transcriptional regulation of target genes, thereby influencing developmental processes and tissue homeostasis.

Product Image Gallery
Western blot analysis of extracts on A431, K562, HepG2 cells, using Smad4 Mouse Monoclonal Antibody (EAB22357) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue,

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol