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Location：Home > Antibodies > Primary Antibodies > Polyclonal Antibodies
ALKBH5 Rabbit Polyclonal Antibody
Catalog #：EAB12086
Datasheet
  SKU-Pack Size Availability Size Price
EAB12086-30UL In Stock 30ul ￥890.00
EAB12086-100UL In Stock 100ul ￥1990.00
EAB12086-200UL In Stock 200ul ￥3390.00
If you want to get a larger packsize, Please contact your local distributor or
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2 / F, 128 malianwa North Road, Haidian District, E-mail：   mrkbio@163.com 
China Beijing China Website： www.mrkbio.com
Product Information
Applications WB, IHC-P, IF, ELISA
Species Reactivity Human, Mouse
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000　
IHC-P=1:50-300　
IF=1:50-300
MW (kDa) 51
Conjugate Unconjugate
Specificity ALKBH5 Rabbit Polyclonal Antibody detects endogenous levels of ALKBH5 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr-Horse All-All Species Expected
Product Bioinformatics
Synonym(s) AlkB homolog 5; ABH5; OFOXD; OFOXD1; ALKBH5
Gene Aliases ALKBH5
UniProt ID

Q6P6C2
Entrez Gene ID

54890
Product Description

ALKBH5 also known as ABH5, OFOXD1 is a Dioxygenase that demethylates RNA by oxidative demethylation. ALKBH5 is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo. Enables mRNA N6-methyladenosine dioxygenase activity and molecular condensate scaffold activity. Involved in membraneless organelle assembly; post-transcriptional regulation of gene expression; and response to hypoxia. Acts upstream of or within regulation of mRNA export from nucleus and regulation of mRNA processing. Located in Golgi apparatus; cytosol; and nuclear speck. Is active in paraspeckles. 
Product Image Gallery
Western blot analysis of extracts on SW480 cells, using ALKBH5 Rabbit Polyclonal Antibody (EAB12086) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Predicted band size: 51 kDa; Observed band size: 40-44 kDa
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using ALKBH5 Rabbit Polyclonal Antibody (EAB12086) at 1:200 dilution.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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