Monoclonal Antibodies - ADAR1 Mouse Monoclonal Antibody

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ADAR1 Mouse Monoclonal Antibody

Catalog #：EAB22311

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22311-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, FC, ELISA
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000 FC=1:50-200
MW (kDa)	136
Conjugate	Unconjugate
Specificity	ADAR1 Mouse Monoclonal Antibody detects endogenous levels of ADAR1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Adenosine deaminase RNA specific; DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP; ADAR
Gene Aliases	ADAR
UniProt ID	P55265
Entrez Gene ID	103

Product Description

ADAR1 plays a crucial role in RNA editing by converting adenosine to inosine in double-stranded RNA, essential for gene expression regulation and cellular homeostasis maintenance. This editing process is particularly important in immune response, as ADAR1 can modulate viral RNA recognition, influencing host response to infections. ADAR1 is expressed from an interferon-response promoter and features a Z-DNA/Z-RNA binding domain at N-terminus, vital for RNA editing function. ADAR1′s ability to bind short interfering RNA (siRNA) suggests potential limitation of siRNA-mediated gene silencing in mammalian cells, making ADAR1 a critical player in RNA biology and therapeutic applications.

Product Image Gallery
Western blot analysis of extracts on Romas, K562 cells, using ADAR1 Mouse Monoclonal Antibody (EAB22311) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Predicted band size: 136 kDa; Observed band size: 110 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol