P10916 

MYL2 also known MLC2, MLC2v is a major sarcomeric protein in mammalian striated muscle. MYL2 is predominantly located in adult cardiac ventricle muscle, where MYL2 forms part of a hexameric complex essential for proper heart functioning. Precise localization of MYL2 is vital for maintaining structural integrity and contractile efficiency of cardiac tissue, and MYL2 expression is a key marker for cardiac chamber specification. Notably, mutations in MYL2 have been linked to various forms of hypertrophic cardiomyopathy, underscoring MYL2′s importance in cardiac health and disease.