Polyclonal Antibodies - PRP19 Rabbit Polyclonal Antibody

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PRP19 Rabbit Polyclonal Antibody

Catalog #：EAB12009

SKU-Pack Size	Availability	Size	Price
EAB12009-30UL	In Stock	30ul	€115.70
EAB12009-100UL	In Stock	100ul	€258.70
EAB12009-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	55
Conjugate	Unconjugate
Specificity	PRP19 Rabbit Polyclonal Antibody detects endogenous levels of PRP19 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Pre-mRNA processing factor 19; PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200; PRPF19
Gene Aliases	PRPF19
UniProt ID	Q9UMS4
Entrez Gene ID	27339

Product Description

PRP19 is part of the PRP19-associated complex, which is vital for the stable association of U5 and U6 snRNPs with the spliceosome after the release of U4. PRP19 interaction with the spliceosome not only facilitates the remodeling of the U6/5 splice site interaction but also leads to the destabilization of Lsm proteins, allowing U6 to engage more effectively with the intron sequence. Understanding PRP19 function is important because any dysregulation in splicing can lead to various diseases, including cancer and neurodegenerative disorders.

Product Image Gallery
Western blot analysis of extracts on Jurkat, COLO205 cells, using PRP19 Rabbit Polyclonal Antibody (EAB12009) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemistry of paraffin-embedded Human gastric cancer tissue, using PRP19 Rabbit Polyclonal Antibody (EAB12009) at 1:100 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol